Buy Abilify Online

Active Ingredient: Aripiprazole
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What is Abilify?

Abilify (Aripiprazole) - antipsychotic agent for the treatment of mental disorders of various genesis. The drug has serious side effects, so it is taken only as prescribed by a doctor.

Abilify is available in the form of tablets for oral administration with an active substance content of 5, 10, 15, 20, 30 mg. One cell package contains 7 pcs., in a cardboard box - 4 blisters. Country of origin - Germany/UK/USA.

The tablets are rectangular in shape with rounded edges, the color corresponds to a certain dosage:

  • Blue – 5 mg:
  • Pink – 10, 30 mg;
  • Yellow – 15 mg;
  • White – 20 mg.

The main active substance of the drug Abilify is Aripiprazole, an atypical antipsychotic. It belongs to a new class of neuroleptics, has a more "mild" effect on the nervous system, is easily tolerated by the body. Some clinicians consider Aripiprazole to be a third-generation antipsychotic, considering it the first representative of the class of antipsychotics dopamine-serotonin stabilizers.

Auxiliary components of Abilify:

  • Lactose monohydrate - a substance for pressing tablets;
  • MCC - emulsifier;
  • Magnesium stearate - lubricant for the production of solid dosage forms;
  • Giprolose is a structure - forming agent;
  • Corn starch - filler;
  • Blue shiny FCF, iron oxide yellow and red are food dyes.

Pharmacological properties

Abilify is a neuroleptic of versatile effects on the body. It causes a calming effect by inhibiting the reaction to external stimuli. The drug weakens psychomotor agitation, feelings of anxiety, fear, anger.

Abilify suppresses aggression, hallucinations and other psychopathological syndromes. The remedy causes a state of drowsiness, promotes the rapid onset of sleep. In combination with sedatives and hypnotics, it enhances their effect.

Aripiprazole, corresponding to its efficacy and efficacy, is characterized by a low risk of metabolic disorders, as well as EPR (possibly tardive dyskinesia) and hyperprolactinemia, compromising relatively cheap TN. The profile of undesirable effects of aripiprazole is important given the fact that more than a third of schizophrenia patients have to be treated with antipsychotics for many years. This makes it possible to put aripiprazole in the first row of the choice of supportive treatment.

Abilify tablets are stored in a dry room at a temperature of 15 to 30 ° C. Shelf life is 3 years.

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Indications for use

The safety and tolerability of treatment is a priority of modern medicine and the choice of any medicine. Abilify is prescribed to patients diagnosed with schizophrenia to relieve acute paranoid seizures, as well as to maintain a mental state during post-schizophrenic depression.

Tablets are prescribed to patients with type 1 bipolar disorder for the treatment and prevention of relapse. The remedy facilitates the course of chronic mental pathology, which is often the cause of disability, reduces the severity of episodes of mania and depression.

Abilify is prescribed as part of the complex treatment of manic states, antidepressant therapy.

For the treatment of exacerbations, supportive and long-term anti-relapse therapy of schizophrenia, other psychotic disorders with productive symptoms (delirium, hallucinations, automatism) and/or negative symptoms (emotional flatness, decreased social activity, impoverishment of speech), as well as concomitant affective disorders;

For the treatment of acute mixed or manic seizures in bipolar affective disorder without / with psychotic manifestations, without / with rapid phase change.

Contraindications

Neuroleptic is not prescribed for children and adolescents under 18 years of age. The drug is contraindicated in cases of high sensitivity to certain components, the presence of a history of severe allergic reactions.

With caution, Abilify is prescribed for such conditions:

  • Chronic vascular and heart diseases, heart attack, coronary artery disease, cardiac muscle conduction blockages;
  • Cerebrovascular pathology is a violation of blood circulation in the brain;
  • Conditions dangerous by an increase in blood pressure – dehydration, a decrease in the volume of circulating blood;
  • Convulsive seizures in the anamnesis;
  • The circumstances provoking hyperthermia are intense physical activity, taking antiemetic drugs, heat stroke;
  • Risk of aspiration pneumonia – esophageal motility failures;
  • Obesity, unfavorable family history regarding diabetes mellitus.

Method of application and dosage

Tablets are taken once a day, regardless of the meal. The maximum daily dose is 30 mg. Patients require periodic examination for the expediency of supportive treatment.

Schizophrenia - Initial dosage – 10-15 mg / day, maintenance - 15 mg / day.

Bipolar disorder, manic states - The initial dose is 15 mg / day. The increase in dosage should be gradual, no more than once every 24 hours. Therapeutic course - 1-3 months.

Depressive disorder, together with antidepressants - The initial dose is 5 mg / knock, the maximum is 15 mg / knock.

As part of complex treatment - 15-30 mg / day.

Side effects Possible negative effects after taking Abilify

Nervous system: Headaches, sleep disturbance, daytime drowsiness, pathological restlessness, tremor of the extremities, decreased mood, psychomotor agitation, aggressiveness, suicidal tendencies, confusion, manic moods, apathy, decreased attention, memory loss, tingling sensation under the skin.

Euphoria, delirium, immobility of joints, soreness of body movements, decreased reflexes, seizures, speech disorders, obsessive thoughts, depression of consciousness or its complete loss.

Heart and blood vessels: Palpitations, excessive drop in blood pressure, feeling of your own heartbeat, atrial fibrillation.

Hemorrhages, heart attack, heart failure, cardiac arrest, blockage of large veins by blood clots, ischemia of brain tissues, fainting, intracranial bleeding, a sharp increase in blood pressure.

Gastrointestinal tract: Loss of appetite, nausea not related to eating, belching, vomiting, dyspeptic disorders, bloating, stool disorders, dry mouth or hypersecretion of saliva, difficulty swallowing, swelling of the tongue, inflammation of the intestine, fungal lesion of the oral mucosa.

Inflammation of the tongue, esophagus, vomiting with blood, ulceration of the intestinal mucosa, intestinal bleeding, persistent damage to the lips (cracks, maceration), liver enlargement, jaundice, hepatitis.

Musculoskeletal system: Muscle, joint pain, arthritis, rigidity, spasms of large muscles, chronic damage to muscle tissue on a nervous basis, inflammation of joint bags.

Extreme degree of destruction of muscle tissue, inflammation and dystrophy of tendons.

Respiratory system: Shortness of breath, hiccups, pneumonia, larynx, nosebleeds. Increased production of sputum in the bronchi, dry nose, hemoptysis, pulmonary edema, blockage of the pulmonary artery, respiratory arrest, lack of oxygen.

Urinary system: Frequent urination, erythrocytes, leukocytes, protein in the urine, inflammation of the bladder, kidney failure. Burning sensation during urination, kidney stones, urinary incontinence.

Exchange of things: Dehydration, weight loss, thirst, increased fat, cholesterol, urea in the blood. Iron deficiency anemia, obesity, gout, increased blood glucose, impaired carbohydrate metabolism, diabetic coma.

Sensory organs: Photophobia, blurred vision, eyelid inflammation, pain, tinnitus, otitis media, loss of taste. Cataracts, rhythmic blinking, lacrimation, decreased visual acuity, double vision, intraocular hemorrhages, inflammation of the auricle, deafness.

Sexual system: Thrush, lack of menstruation, premature ejaculation. Chest pain, profuse uterine bleeding, anorgasmia, burning sensation in the perineal area, cervical erosion, prolonged painful erection (more than 4 hours).

Dermatology: Itching, peeling, inflammation of the sebaceous glands, hair follicles. Eczema, psoriasis, dermatitis, excessive sweating, dandruff, hair loss.

Allergology: Urticaria, Quincke's edema, laryngeal spasm.

General reactions of the body. Chronic fatigue, malaise, lethargy, trembling in the body, flu-like syndrome. Swelling of the limbs, face, sore throat, back, neck, chest tension, heaviness in the head, stiffness in the jaws

Overdose

In clinical practice, cases of unintentional and intentional overdose with Abilify tablets have been recorded. A single dose of up to 1260 mg does not pose a threat to life.

Symptoms of toxic drug poisoning:

  • Increased blood pressure;
  • Rapid heartbeat;
  • Drowsiness;
  • Loss of consciousness;
  • Lethargic sleep.

Treatment consists in maintaining the work of vital organs - heart, kidneys, brain, liver, lungs. The patient is regularly monitored by an ECG, provides patency of the trachea, bronchi, saturation of the body with oxygen (oxygenation, ventilation). Hemodialysis to remove Abilifai from the blood is ineffective.

Special instructions

Long-term treatment with a neuroleptic in patients with chronic psychoses requires careful medical supervision, because the drug causes suicidal moods. In order to avoid overdose, therapy begins with the minimum effective doses.

The longer the treatment, the higher the risk of developing tardive dyskinesia - violent involuntary movements. When the first symptoms of pathology occur, the dose should be reduced or Abilify should be canceled.

In elderly people with senile dementia, the drug increases the risk of mortality. Patients with Alzheimer's disease often have cardiovascular disorders that lead to mortality – heart attack, cerebral circulation failures. Therefore, such patients are not recommended to prescribe Abilify for the treatment of psychoses.

Increased sugar and blood oxidation are dangerous diabetic coma, a direct threat to life. Therefore, patients with diabetes mellitus are required to undergo regular glycemic control.

People who are at risk for obesity, diabetes mellitus are tested for blood glucose levels throughout the treatment. Systematically monitor the appearance of symptoms such as frequent urination, insuperable thirst, eating disorders, general weakness.

Use During pregnancy and lactation

Clinical studies of the appointment of Abilify in obstetrics and gynecology have not been conducted. There is no data on the absolute safety of neuroleptics for pregnant women. The drug may be prescribed during pregnancy, provided that the potential benefit to the woman exceeds the risk to the development of the fetus.

There is no data on whether the active substance is excreted in breast milk. Therefore, it is not recommended to prescribe Abilify during lactation.

Use In childhood: The drug is contraindicated for use in pediatric practice. Abilify is not prescribed for children under 18 years of age.

Use In the elderly: People over 65 years of age do not need to adjust the treatment regimen.

With impaired renal function: In case of renal insufficiency, the dose of the drug Abilify is not reduced.

With impaired liver function: People with a history of hepatic dysfunction do not need to adjust the dose.